- Schizophrenia
- Schlocks
- School Bus Fun
- School Days HQ
- School House Shuffle
- School of Talent: SUZU-ROUTE
- School Tycoon
- Schrödinger’s Cat And The Raiders Of The Lost Quark
- Science Girls
- Scooby Doo! & Looney Tunes Cartoon Universe: Adventure
- Scooby-Doo First Frights
- Scooby-Doo! and the Spooky Swamp
- Scoot Kaboom and the Tomb of Doom
- Scooter War3Z
- Scorch
- Scott in Space v1.16.14.29
- Scourge of War: Gettysburg
- Scourge of War: Ligny (Inclu ALL DLC)
- Scourge of War: Wavre
- Scourge: Outbreak
- ScourgeBringer
- SCP 087. Re
- SCP Sculpture Hentai Edition
- SCP-087 VR Survivor
- SCP: Blackout
- SCP: Doki Doki Anomaly
- SCP: Undeads Winter’s
- SCRABBLE – The Classic Word Game
- Scrap Galaxy
- Scrap Garden v1.25
- Scrap Mechanic v0.3.5
- Scrap Mechanic v0.5.1.659
- SCRAP RUSH!!
- Scraper: First Strike
- Scraper: Gauntlet
- Scrapnaut
- Scrapper
- Scraps: Modular Vehicle Combat v0.5.6.1
- Scratches
- Screamer 4×4 (GOG)
- Screaming Eagles
- Screencheat v3.3.0
- Screensavers VR
- Screeps
- SCREW-NUT
- Scribble Ships v1.01
- Scribble Space
- Scribblenauts Unlimited
- Scribblenauts Unmasked A DC Comics Adventure
- Scrutinized
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